Comfort food at its finest – there’s nothing quite like a warm, gooey casserole on a chilly day. And when it comes to satisfying our cravings for something rich and indulgent, few dishes deliver like Cream of Chicken Casserole. With its creamy sauce, tender chicken, and comforting textures, this classic recipe is a staple in many households.
But why settle for just one version when you can have 20? From classic combinations to bold twists, we’ve rounded up the creamiest, most mouthwatering Cream of Chicken Casserole recipes out there. Whether you’re a fan of cheesy, broccoli-filled casseroles or spicy, south-of-the-border-inspired dishes, there’s something for everyone in this collection.
In the following pages, we’ll take you on a journey through the world of Cream of Chicken Casserole, highlighting the best of the best and sharing our top tips for making each recipe a success. So go ahead, grab your mixing bowl and your favorite casserole dish – it’s time to get cooking!
Classic Cream of Chicken and Rice Casserole
This comforting casserole is a timeless favorite that’s perfect for weeknight dinners or special occasions. A creamy sauce, tender chicken, and flavorful rice come together in a satisfying dish that’s sure to please.
Ingredients:
– 1 1/2 cups cooked white rice
– 1 1/2 pounds boneless, skinless chicken breast or thighs, cut into 1-inch pieces
– 2 tablespoons butter
– 1 medium onion, chopped
– 1 cup frozen peas and carrots
– 1 cup cream of chicken soup
– 1/2 cup milk
– Salt and pepper to taste
– 1 cup shredded cheddar cheese (optional)
Instructions:
1. Preheat oven to 350°F.
2. In a large skillet, melt butter over medium-high heat. Add chicken and cook until browned, about 5-7 minutes. Remove from heat and set aside.
3. In the same skillet, add chopped onion and cook until softened, about 3-4 minutes.
4. In a separate bowl, combine cooked rice, cream of chicken soup, milk, salt, and pepper. Stir until well combined.
5. Add cooked chicken, peas and carrots, and shredded cheese (if using) to the rice mixture. Mix until everything is coated.
6. Pour the casserole mixture into a 9×13-inch baking dish and top with additional shredded cheese if desired.
7. Bake for 25-30 minutes or until hot and bubbly.
Cheesy Broccoli and Cream of Chicken Casserole
This Cheesy Broccoli and Cream of Chicken Casserole is a comforting, satisfying dish that’s perfect for a weeknight dinner or special occasion. With its creamy sauce, tender broccoli, and rich chicken flavor, it’s sure to become a family favorite.
Ingredients:
– 1 1/2 cups cooked chicken, shredded
– 3 cups broccoli florets
– 1 cup cream of chicken soup
– 1/2 cup milk
– 1 cup shredded cheddar cheese
– 1/4 cup grated Parmesan cheese
– 1 teaspoon dried thyme
– Salt and pepper to taste
– 6-8 crackers, crushed (for topping)
Instructions:
1. Preheat oven to 350°F.
2. In a large mixing bowl, combine chicken, broccoli, cream of chicken soup, milk, cheddar cheese, Parmesan cheese, and thyme. Mix well.
3. Pour the mixture into a 9×13 inch baking dish.
4. Top with crushed crackers.
5. Bake for 30-35 minutes or until golden brown.
Cooking Time: 30-35 minutes
Spicy Southwest Cream of Chicken Casserole
A flavorful twist on the classic casserole, this Spicy Southwest Cream of Chicken Casserole combines the richness of cream with the boldness of Southwestern spices. Perfect for a weeknight dinner or a special occasion.
Ingredients:
– 1 1/2 pounds boneless, skinless chicken breasts, cut into bite-sized pieces
– 1 medium onion, diced
– 2 cloves garlic, minced
– 1 red bell pepper, diced
– 1 can (10.5 oz) cream of chicken soup
– 1/2 cup heavy cream
– 1 teaspoon ground cumin
– 1/2 teaspoon smoked paprika
– 1/4 teaspoon cayenne pepper
– Salt and pepper to taste
– 1 cup shredded cheddar cheese
– 1/2 cup crushed tortilla chips
– Fresh cilantro leaves for garnish (optional)
Instructions:
1. Preheat oven to 375°F.
2. In a large skillet, sauté chicken, onion, garlic, and bell pepper until cooked through.
3. Stir in cream of chicken soup, heavy cream, cumin, smoked paprika, and cayenne pepper. Bring to a simmer.
4. Pour the mixture into a 9×13-inch baking dish.
5. Top with shredded cheese and crushed tortilla chips.
6. Bake for 25-30 minutes or until hot and bubbly.
Cooking Time: 25-30 minutes
Cream of Chicken and Stuffing Casserole
A comforting twist on traditional casserole, this recipe combines the savory flavors of chicken, cream, and stuffing with a crunchy breadcrumb topping. Perfect for a cozy weeknight dinner or a special occasion.
Ingredients:
– 1 pound boneless, skinless chicken breasts, cut into 1-inch pieces
– 2 cups cubed white bread (day-old)
– 1/4 cup chopped celery
– 1/4 cup chopped onion
– 2 cloves garlic, minced
– 1 teaspoon dried thyme
– 1/2 teaspoon paprika
– 1/2 cup heavy cream
– 1/2 cup chicken broth
– 1 tablespoon butter, melted
– 1/2 cup breadcrumbs
– Salt and pepper to taste
Instructions:
1. Preheat oven to 375°F (190°C).
2. In a large skillet, sauté chicken, celery, onion, garlic, thyme, and paprika until the chicken is cooked through.
3. In a separate bowl, combine bread, cream, broth, melted butter, and seasonings.
4. Add cooked chicken mixture to bread mixture; mix well.
5. Transfer to a 9×13 inch baking dish and top with breadcrumbs.
6. Bake for 25-30 minutes or until the casserole is golden brown.
Cooking Time: 25-30 minutes
Loaded Potato and Cream of Chicken Casserole
This casserole combines the creamiest chicken filling with crispy potatoes, gooey cheese, and a hint of savory flavor. Perfect for a cozy night in or a family gathering.
Ingredients:
– 2 large potatoes, peeled and thinly sliced
– 1 (10.5 oz) can of Cream of Chicken soup
– 1/2 cup milk
– 1 cup shredded cheddar cheese
– 1/4 cup butter, melted
– 1 pound cooked chicken, diced
– 1 teaspoon paprika
– Salt and pepper to taste
Instructions:
1. Preheat oven to 350°F (180°C).
2. In a large bowl, combine sliced potatoes, Cream of Chicken soup, milk, shredded cheese, and melted butter. Mix well.
3. Add cooked chicken, paprika, salt, and pepper; stir until combined.
4. Transfer the mixture to a 9×13-inch baking dish.
5. Bake for 35-40 minutes or until potatoes are golden brown and casserole is hot and bubbly.
Cooking Time: 35-40 minutes
Serve Hot
Cream of Chicken and Wild Rice Casserole
Cream of Chicken and Wild Rice Casserole
A comforting and flavorful casserole that combines the richness of cream with the nutty taste of wild rice, perfect for a cozy evening meal.
Ingredients:
– 1 1/2 cups cooked wild rice
– 1 can (10 3/4 oz) of Cream of Chicken soup
– 1 cup heavy cream
– 1/2 cup shredded cheddar cheese
– 1/2 cup diced cooked chicken breast
– 1/2 teaspoon paprika
– Salt and pepper to taste
Instructions:
1. Preheat oven to 350°F (175°C).
2. In a large mixing bowl, combine wild rice, Cream of Chicken soup, heavy cream, shredded cheese, diced chicken, and paprika. Mix well.
3. Pour the mixture into a 9×13-inch baking dish.
4. Bake for 25-30 minutes or until hot and bubbly.
5. Serve warm and enjoy!
Cooking Time: 25-30 minutes
Green Bean and Cream of Chicken Casserole
A comforting casserole that combines tender green beans with the rich flavors of cream of chicken soup, perfect for a weeknight dinner or potluck gathering. This easy-to-make dish is sure to please even the pickiest eaters.
Ingredients:
– 1 pound fresh green beans, trimmed
– 1 cup cream of chicken soup
– 1/2 cup milk
– 1/4 cup shredded cheddar cheese
– 1/4 cup chopped onion
– 1/2 teaspoon black pepper
– 1/2 cup French-fried onions
Instructions:
1. Preheat oven to 350°F.
2. Cook green beans according to package instructions until tender. Drain and set aside.
3. In a separate saucepan, combine cream of chicken soup, milk, and shredded cheese. Heat over medium heat, stirring constantly, until smooth.
4. Add cooked green beans, chopped onion, and black pepper to the saucepan. Stir until combined.
5. Pour mixture into a 9×13-inch baking dish. Sprinkle French-fried onions on top.
6. Bake for 25-30 minutes or until casserole is hot and bubbly.
Cooking Time: 25-30 minutes
Cream of Chicken and Cornbread Casserole
This classic casserole combines the creamiest cream of chicken soup with a crunchy cornbread topping, perfect for a cozy night in. A delicious twist on traditional comfort food!
Ingredients:
– 1 1/2 cups cream of chicken soup
– 1 cup milk
– 1/2 cup frozen corn kernels
– 1 cup cooked chicken, diced
– 1 cup cornbread mix
– 1/4 cup butter, melted
– Salt and pepper to taste
Instructions:
1. Preheat oven to 350°F (180°C).
2. In a large mixing bowl, combine cream of chicken soup, milk, and frozen corn kernels. Stir until smooth.
3. Add cooked chicken and stir to combine.
4. Pour mixture into a 9×13-inch baking dish.
5. In a separate bowl, mix together cornbread mix and melted butter. Spread evenly over the casserole.
6. Bake for 35-40 minutes or until cornbread is golden brown.
7. Serve hot and enjoy!
Cooking Time: 35-40 minutes
Bacon and Cream of Chicken Casserole
Bacon and Cream of Chicken Casserole Recipe
Satisfy your comfort food cravings with this creamy, savory casserole featuring crispy bacon and rich cream of chicken soup.
Ingredients:
– 1 lb boneless, skinless chicken breast or thighs, cut into 1-inch pieces
– 6 slices of bacon, diced
– 1 can (10.5 oz) of Cream of Chicken Soup
– 1 cup of milk
– 1/2 cup of shredded cheddar cheese
– 1/4 cup of chopped fresh parsley
– 1 tsp of dried thyme
– Salt and pepper to taste
– 6-8 medium-sized potatoes, peeled and thinly sliced
Instructions:
1. Preheat oven to 350°F (175°C).
2. Cook the bacon in a skillet until crispy; set aside.
3. In the same skillet, add the chicken and cook until browned; remove from heat.
4. In a large mixing bowl, combine cooked chicken, Cream of Chicken Soup, milk, shredded cheese, parsley, thyme, salt, and pepper. Mix well.
5. Grease a 9×13-inch baking dish with butter or cooking spray. Arrange half the potato slices in the dish.
6. Pour the chicken mixture over the potatoes, followed by the remaining potatoes.
7. Top with crispy bacon pieces.
8. Bake for 45-50 minutes, or until potatoes are tender and casserole is golden brown.
Cooking Time: 45-50 minutes
Cream of Chicken and Pasta Bake
A comforting, satisfying casserole that combines tender pasta, juicy chicken, and a rich creamy sauce, perfect for a weeknight dinner or special occasion.
Ingredients:
– 8 oz pasta (such as penne or fusilli)
– 1 lb boneless, skinless chicken breast, cut into bite-sized pieces
– 2 cups mixed vegetables (e.g., bell peppers, carrots, mushrooms)
– 1 cup cream of chicken soup
– 1/2 cup shredded cheddar cheese
– 1/4 cup grated Parmesan cheese
– 1/2 teaspoon dried thyme
– Salt and pepper to taste
– 1 tablespoon olive oil
Instructions:
1. Preheat oven to 375°F (190°C).
2. Cook pasta according to package instructions; set aside.
3. In a large skillet, sauté chicken, vegetables, and cream of chicken soup until the chicken is cooked through and the sauce is smooth.
4. Combine cooked pasta, chicken mixture, and shredded cheese in a 9×13-inch baking dish.
5. Top with grated Parmesan cheese and drizzle with olive oil.
6. Bake for 25-30 minutes or until the casserole is hot and bubbly.
Cooking Time: 25-30 minutes
Spinach and Cream of Chicken Casserole
This comforting casserole combines the richness of cream with the earthiness of spinach and the savory flavor of chicken, making it a perfect weeknight dinner option.
Ingredients:
– 1 pound boneless, skinless chicken breast or thighs, cut into bite-sized pieces
– 2 cups fresh spinach leaves
– 1 cup cream of chicken soup
– 1/2 cup heavy cream
– 1/2 cup shredded cheddar cheese
– 1/4 cup milk
– 1 teaspoon dried thyme
– Salt and pepper to taste
– 1 1/2 cups cooked white rice
Instructions:
1. Preheat oven to 350°F (180°C).
2. Cook chicken, spinach, and thyme in a skillet until chicken is cooked through.
3. In a separate bowl, combine cream of chicken soup, heavy cream, and milk.
4. Add cooked chicken mixture to the soup mixture; stir to combine.
5. Pour mixture over rice in a 9×13 inch baking dish.
6. Top with shredded cheddar cheese.
7. Bake for 25-30 minutes or until golden brown.
Cooking Time: 25-30 minutes
Cream of Chicken and Biscuit Casserole
This comforting casserole combines tender chicken, creamy sauce, and flaky biscuits for a satisfying meal that’s perfect for any occasion. With just a few simple steps, you’ll be enjoying a warm, golden-brown delight in no time!
Ingredients:
– 1 1/2 cups cooked chicken breast or thighs
– 1 can (10.5 oz) of Cream of Chicken soup
– 1 cup milk
– 1/2 cup shredded cheddar cheese
– 1/4 cup butter, softened
– 1 package of biscuit mix (6-8 biscuits)
– Salt and pepper to taste
Instructions:
1. Preheat oven to 375°F.
2. In a large mixing bowl, combine cooked chicken, Cream of Chicken soup, milk, and shredded cheese. Mix until smooth.
3. Pour the mixture into a 9×13-inch baking dish.
4. Top with biscuit mix, following package instructions for preparation.
5. Dot the top of the casserole with softened butter.
6. Bake for 35-40 minutes or until biscuits are golden brown and casserole is hot and bubbly.
Cooking Time: 35-40 minutes
Mexican-Style Cream of Chicken Casserole
Mexican-Style Cream of Chicken Casserole: A flavorful twist on a classic comfort food dish.
Ingredients:
– 1 pound boneless, skinless chicken breast or thighs, cut into 1-inch pieces
– 1 can (10.5 oz) of cream of chicken soup
– 1/2 cup heavy cream
– 1 tablespoon olive oil
– 1 small onion, diced
– 1 clove garlic, minced
– 1 teaspoon cumin
– 1/2 teaspoon paprika
– Salt and pepper to taste
– 6-8 corn tortillas
– Shredded Monterey Jack cheese (optional)
– Fresh cilantro leaves for garnish (optional)
Instructions:
1. Preheat oven to 350°F.
2. In a large skillet, heat the olive oil over medium-high heat. Add the chicken and cook until browned, about 5-7 minutes. Remove from heat and set aside.
3. In the same skillet, add the diced onion and minced garlic. Cook until softened, about 3-4 minutes.
4. Stir in the cumin, paprika, salt, and pepper. Add the cream of chicken soup and heavy cream. Bring to a simmer and let cook for 2-3 minutes or until slightly thickened.
5. In a large mixing bowl, combine the cooked chicken, soup mixture, and tortillas. Mix well to combine.
6. Transfer the mixture to a 9×13-inch baking dish and top with shredded cheese (if using).
7. Bake for 25-30 minutes or until the casserole is hot and bubbly.
Enjoy your delicious Mexican-Style Cream of Chicken Casserole!
Cream of Chicken and Mushroom Casserole
This comforting casserole combines the rich flavors of chicken, mushrooms, and creamy sauce, perfect for a satisfying weeknight dinner or special occasion. With its golden-brown top and savory aroma, it’s sure to become a family favorite.
Ingredients:
– 1 pound boneless, skinless chicken breasts, cut into 1-inch pieces
– 2 cups mixed mushrooms (button, cremini, shiitake), sliced
– 1 medium onion, chopped
– 2 cloves garlic, minced
– 1 cup cream of chicken soup
– 1/2 cup milk
– 1 teaspoon dried thyme
– Salt and pepper to taste
– 1 cup shredded cheddar cheese
– 1/4 cup breadcrumbs
Instructions:
1. Preheat oven to 350°F (180°C).
2. In a large skillet, sauté chicken, mushrooms, onion, and garlic until cooked through.
3. In a separate bowl, combine cream of chicken soup, milk, thyme, salt, and pepper. Stir until smooth.
4. In a greased 9×13-inch baking dish, arrange the cooked chicken mixture, followed by the creamy sauce.
5. Top with shredded cheese and breadcrumbs. Bake for 25-30 minutes or until golden brown.
Cooking Time: 25-30 minutes
Zucchini and Cream of Chicken Casserole
This creamy casserole is a perfect summer side dish or main course, featuring the flavors of zucchini, chicken, and cheese. With its ease of preparation and delicious taste, it’s sure to become a family favorite!
Ingredients:
– 1 medium zucchini, sliced
– 1 cup cooked chicken breast, diced
– 1 cup cream of chicken soup
– 1/2 cup milk
– 1 cup shredded cheddar cheese
– 1/4 cup chopped fresh parsley
– 1 teaspoon paprika
– Salt and pepper to taste
– 6-8 crackers (e.g., Ritz or saltines)
Instructions:
1. Preheat oven to 350°F.
2. In a large mixing bowl, combine zucchini, chicken, cream of chicken soup, milk, shredded cheese, parsley, paprika, salt, and pepper. Mix well.
3. Pour mixture into a 9×13-inch baking dish.
4. Top with crackers.
5. Bake for 30-35 minutes or until casserole is hot and bubbly.
Cooking Time: 30-35 minutes
Cream of Chicken and Quinoa Casserole
A hearty and comforting casserole that combines the creamy richness of chicken soup with the nutty flavor of quinoa, perfect for a weeknight dinner or weekend gathering.
Ingredients:
– 1 pound boneless, skinless chicken breast or thighs
– 2 cups cooked quinoa
– 2 cups cream of chicken soup
– 1 cup shredded cheddar cheese
– 1/2 cup milk
– 1/4 cup chopped fresh parsley
– Salt and pepper to taste
Instructions:
1. Preheat oven to 350°F (180°C).
2. Cook the quinoa according to package instructions.
3. In a separate pot, heat the cream of chicken soup with milk over medium heat until smooth.
4. Add cooked chicken, shredded cheese, and chopped parsley to the soup mixture; stir well.
5. Combine cooked quinoa with the chicken soup mixture and season with salt and pepper.
6. Transfer the mixture to a 9×13 inch baking dish and bake for 25-30 minutes or until hot and bubbly.
Cooking Time: 25-30 minutes
Cauliflower and Cream of Chicken Casserole
This creamy casserole combines the flavors of roasted cauliflower, tender chicken, and a rich cream sauce, perfect for a comforting weeknight dinner.
Ingredients:
– 1 head of cauliflower, broken into florets
– 1 pound boneless, skinless chicken breast or thighs, cut into bite-sized pieces
– 2 tablespoons butter
– 1 cup cream of chicken soup
– 1/2 cup milk
– 1 teaspoon dried thyme
– Salt and pepper to taste
– 1 cup shredded cheddar cheese (optional)
Instructions:
1. Preheat oven to 375°F.
2. In a large skillet, melt butter over medium-high heat. Add chicken and cook until browned, about 5-7 minutes. Remove from heat and set aside.
3. In the same skillet, add cauliflower and cook until tender, about 5-7 minutes.
4. In a separate bowl, mix cream of chicken soup, milk, thyme, salt, and pepper. Pour over cooked cauliflower and stir to combine.
5. Add cooked chicken to the skillet and stir to combine with the cauliflower mixture.
6. Transfer mixture to a 9×13 inch baking dish and top with shredded cheddar cheese (if using).
7. Bake for 20-25 minutes or until hot and bubbly.
Cooking Time: 25-30 minutes
Cream of Chicken and Sweet Potato Casserole
This classic casserole combines the comfort of sweet potatoes with the richness of cream, chicken, and cheese. Perfect for a weeknight dinner or special occasion, this dish is sure to become a family favorite.
Ingredients:
– 1 large sweet potato, peeled and diced
– 1 can (14.5 oz) cream of chicken soup
– 1/2 cup heavy cream
– 1 cup shredded cheddar cheese
– 1/2 cup cooked, shredded chicken breast
– 1/4 teaspoon paprika
– Salt and pepper to taste
– 6-8 crackers or croutons (optional)
Instructions:
1. Preheat oven to 350°F.
2. In a large mixing bowl, combine sweet potatoes, cream of chicken soup, heavy cream, cheese, chicken, paprika, salt, and pepper. Mix until well combined.
3. Grease a 9×13-inch baking dish with butter or cooking spray.
4. Pour the casserole mixture into the prepared baking dish.
5. Top with crackers or croutons (if using).
6. Bake for 30-35 minutes or until golden brown and hot throughout.
Cooking Time: 30-35 minutes
Herbed Cream of Chicken and Veggie Casserole
A creamy, comforting casserole perfect for a weeknight dinner or special occasion. This recipe combines chicken, vegetables, and herbs in a rich cream sauce.
Ingredients:
– 1 pound boneless, skinless chicken breast or thighs, cut into 1-inch pieces
– 2 cups mixed frozen vegetables (such as peas, carrots, corn)
– 1 medium onion, chopped
– 2 cloves garlic, minced
– 1 cup heavy cream
– 1 teaspoon dried thyme
– 1/2 teaspoon paprika
– Salt and pepper to taste
– 1 cup shredded cheddar cheese
– 1/4 cup breadcrumbs
Instructions:
1. Preheat oven to 375°F (190°C).
2. In a large skillet, cook chicken, onion, and garlic until chicken is cooked through.
3. Add frozen vegetables, heavy cream, thyme, paprika, salt, and pepper. Simmer for 5 minutes or until vegetables are tender.
4. Transfer mixture to a 9×13-inch baking dish. Top with shredded cheese and breadcrumbs.
5. Bake for 20-25 minutes or until top is golden brown and casserole is heated through.
Cooking Time: 25-30 minutes
Cream of Chicken and Egg Noodle Casserole
A comforting, creamy casserole that combines the flavors of chicken, eggs, and noodles.
Ingredients:
– 1 pound boneless, skinless chicken breast or thighs, cut into bite-sized pieces
– 8 ounces egg noodles
– 2 cups cream of chicken soup
– 1/2 cup milk
– 2 large eggs, beaten
– 1/4 cup grated cheddar cheese
– 1/4 teaspoon black pepper
– Salt to taste
Instructions:
1. Preheat oven to 350°F (180°C).
2. Cook egg noodles according to package instructions; drain and set aside.
3. In a large skillet, cook chicken over medium-high heat until browned and cooked through.
4. In a separate bowl, whisk together cream of chicken soup, milk, beaten eggs, salt, and pepper.
5. Combine cooked noodles, chicken, and creamy mixture in a 9×13 inch baking dish.
6. Top with grated cheddar cheese.
7. Bake for 30-35 minutes or until casserole is hot and bubbly.
Cooking Time: 30-35 minutes
Summary
Get cozy with these 20 creamy Cream of Chicken Casserole recipes! From classic comfort food to spicy twists and veggie-packed options, there’s something for everyone. Try adding broccoli and cheese to your casserole, or give one of the many variations featuring potatoes, wild rice, green beans, and more a try. Whether you’re looking for a hearty meal after a long day or a satisfying dish to serve at your next family gathering, these creamy casseroles are sure to hit the spot.
Sophia Brennan is the cook and writer behind Go Jack Rabbit Go. She spent years working in Portland’s restaurant world before bringing that same warm, unfussy approach into her home kitchen. These days, she focuses on simple, comforting recipes inspired by real life, family routines, and the rhythm of cooking without overthinking it.
